Bottom Line:
This was well-conducted preliminary research that demonstrates the role of the FUS protein in the androgen response of prostate cancer cells in the laboratory, and in animal models. It also shows that FUS levels are inversely associated with tumour grade in human biopsy samples; in other words, that higher FUS levels were associated with less advanced cancer.
Publication details:
Analysis of media reports around a research study.
We assessed this page using an appraisal instrument developed by Minervation specifically for this project. This approach is still in development, so you should regard the assessments as a general guide. Click here to find out more, or to let us know how you think the approach could be improved.
Reliability comments:
- It is clear who has developed the website and what their objectives are.
- The site reports a robust editorial policy that includes critical appraisal of sources.
- Information is provided by a multidisciplinary team of clinicians.
Usability comments:
- No login is needed to access the site.
- The pages are busy and overloaded with information.
- There are many competing navigational tools and the search engine is error-prone.
Scoring
Reliability
| Item |
Score |
| Is it clear who has developed the web site and what their objectives are? |
3 |
| It is clear who has developed the website and what their objectives are. |
| Does the site report a robust quality control procedure? |
3 |
|
|
| Is the page content checked by an expert? |
3 |
|
|
| Is the page updated regularly? |
3 |
|
|
| Does the page cite relevant sources where appropriate? |
2 |
| More contextual links would be beneficial to the user |
Usability
| Item |
Score |
| Is the site accessible without a login? |
3 |
| No login is needed to access the site. |
| Does the site conform to web Accessibility standards? |
3 |
| The site scores 93% for accessibility. |
| Is the site design clear and transparent? |
2 |
| The pages are busy and overloaded with information. |
| Is the site design consistent from one page to another? |
2 |
| The site design is not consistent. |
| Can users find what they need on the site? |
1 |
| The site is sometimes difficult to navigate and the search engine is error prone. |
| Is the format of information clear and appropriate for the audience? |
2 |
| The text is too complex for a lay audience. |
| Weighted total (Usability + (Reliability x 2)): |
41 |
We score each question out of three where:
| 0 |
= Never or Can't tell |
| 1 |
= Sometimes or partly |
| 2 |
= Mostly |
| 3 |
= Always |
|
Protein "may fight prostate cancer"
