signpost iconFive-alpha-reductase Inhibitors for prostate cancer prevention (Cochrane review)

Bottom Line:

Five-alpha-reductase inhibitor drugs, such as finasteride or dutasteride, reduce the risk prostate cancer in men who have routine prostate cancer screening.

Publication details:

This systematic review concludes that five-alpha-reductase inhibitors reduce prostate cancer risk but may increase the risk of high-grade disease in men who are undergoing regular screening for prostate cancer using prostate specific antigen and digital rectal examination.

We assessed this page using an appraisal instrument developed by Minervation specifically for this project. This approach is still in development, so you should regard the assessments as a general guide. Click here to find out more, or to let us know how you think the approach could be improved.

Reliability comments:

  • The page was published 23 April 2008.
  • The page links to a list of relevant sources.
  • Website content is checked by relevant experts
  • A clear statement about the website developers is required
  • A robust quality control procedure is reported

Usability comments:

  • The left hand submenu could be more prominently displayed.
  • The website does not conform to web accessibility standards
  • Poor layout
  • Confusing and over-complicated for users


Item Score
Is it clear who has developed the web site and what their objectives are? 1
Wiley Interscience appears all over the homepage of the Cochrane Library. There is an About Us section but this is hard to locate.
Does the site report a robust quality control procedure? 3
Is the page content checked by an expert? 3
The page has been checked by an expert.
Is the page updated regularly? 2
The page was published on 23 April 2008.
Does the page cite relevant sources where appropriate? 3
The page cites relevant sources.
Item Score
Is the site accessible without a login? 3
No registration required.
Does the site conform to web Accessibility standards? 0
Lida score 80%
Is the site design clear and transparent? 0
Very cluttered homepage, small font size, too many menu options. Very confusing.
Is the site design consistent from one page to another? 1
Not very consistent.
Can users find what they need on the site? 1
Just about. There is a browsing option but this is difficult to find and use. The search facility is confusing and it is difficult to view search results.
Is the format of information clear and appropriate for the audience? 1
The left hand submenu could be more prominently displayed.
Weighted total (Usability + (Reliability x 2)): 30
We score each question out of three where:
0 = Never or Can't tell
1 = Sometimes or partly
2 = Mostly
3 = Always

Date rated


The Cochrane Library





Publication Type

Systematic review




4.5 stars


0.5  stars

Find: Similar

Contact us about this summary

Your comment or question: